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Newly Discovered Elovanoids Called a “Transformative New Concept of Biology”

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans, has discovered a new class of mediators, or biochemical triggers that he named elovanoids (ELVs). Elovanoids are the first bioactive chemical messengers made from omega-3 very long chain polyunsaturated fatty acid (VLC-PUFAs,n-3) that are released in response to cell injury or when cells are confronted with adversities for survival. This discovery provides the first evidence of the existence of elovanoids and of their significant role in protecting and sustaining retinal pigment epithelial (RPE) and photoreceptor cell survival.